June 2026– date –
-
Naked Mole Rat “Longevity Gene” Transferred to Mice — Lifespan +4.4% — May 2026 Rochester Breakthrough and the Road to Humans
May 10, 2026: University of Rochester team transferred the naked mole rat HMW-HA synthase gene (HAS2) to mice — median lifespan +4.4%, reduced cancer, improved healthspan. Human translation 10-20 years away. Today's longevity basics remain unchanged. -
Eating Grapes Daily Changes Your Skin’s Gene Expression — May 2026 Evidence and the New UV-Defense Frontier
May 2026 ACS Nutrition Science study: daily grape consumption changes human skin gene expression and reduces UV-induced oxidative stress. Resveratrol + polyphenols work at the skin level. Eat with the skin — whole food beats supplements. -
Oral GLP-1 Orforglipron Approved by FDA — Not the Same as Mounjaro: Efficacy, Side Effects, and What It Means
April 1, 2026: U.S. FDA approves orforglipron, the first oral GLP-1 obesity drug with no water or food restrictions. ATTAIN-1 trial: -12.4% weight loss. Hidden Japan story: compound licensed from Chugai for $50M in 2018.
1