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Naked Mole Rat “Longevity Gene” Transferred to Mice — Lifespan +4.4% — May 2026 Rochester Breakthrough and the Road to Humans
May 10, 2026: University of Rochester team transferred the naked mole rat HMW-HA synthase gene (HAS2) to mice — median lifespan +4.4%, reduced cancer, improved healthspan. Human translation 10-20 years away. Today's longevity basics remain unchanged. -
[Features] Cold Plunge — Separating the Hype from the Actual Evidence
Dopamine 250%, brown fat, immune boost — does cold plunging deliver any of this? Mood and alertness Level 2; metabolism and lifespan Level 3-4; counterproductive for hypertrophy. -
[Features] Bryan Johnson’s Blueprint — Scoring 100+ Interventions at Levels 1–4
Bryan Johnson reportedly spends $2M/year on anti-aging. The Blueprint core (sleep, exercise, diet) sits at Level 1 and is worth borrowing; the experimental edges remain Level 3–4. A respectful, evidence-grounded audit. -
[Features] GLP-1 Drugs (Ozempic, Mounjaro) — The Strongest Anti-Obesity Drugs Ever, And Their Real Costs
STEP-1: 14.9% weight loss. SURMOUNT-1: 22.5%. SELECT: 20% CV event reduction. GLP-1 drugs are a real revolution — but rebound, muscle loss, monthly cost, and DIY-market risks are equally real. -
[Features] NMN Just Got EU Safety Approval — What It Means (and What It Doesn’t)
EFSA cleared NMN at up to 300 mg/day as safe in May 2026. That is not the same as proving it works. An independent, ad-free audit of the human evidence at Levels 1-4. -
[Special Feature] XPRIZE Healthspan — Where 40 Teams Stand in the Race for $100 Million
[Special Feature] XPRIZE Healthspan — Where 40 Teams Stand in the Race for $100 Million Highlights of this feature The XPRIZE Healthspan is the largest-ever competition in aging research, with a total prize pool of $110 million (approxim...
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